Research is still being conducted to understand the risks of kratom use, but several safety issues and severe health effects have been identified. Health issues related to kratom can include liver toxicity, seizures, substance use disorder (SUD), and even death. There have also been reported cases of kratom products contaminated with Salmonella and heavy metals that could lead to other illnesses. Newborns exposed to kratom before birth have shown withdrawal symptoms including jitteriness, irritability, and muscle stiffness.